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Cryo-EM in academia and Industry

Monday 29 – Wednesday 31st January, 2024 Heidelberg, Germany

CryoSol-World is proud sponsor of this year’s EMBL Industry Workshop in the year of EMBL’s 50th anniversary. You can our new CEO Michiel Peters and product Manager Rene Henderikx all days. Make sure to find our VitroJet experts at the CryoSol-World booth and join the poster session Monday evening at 18:30 and learn more about:

VitroJet: ice thickness control and measurement for time-efficient single particle structure determination

René Henderikx will talk you up to speed about his latest research to underpin how the VitroJet gives you control of the ice thickness and enables ice thickness measurement.

Part of the abstract

As learned in cryo-electron microscopy structure determination, embedding biomolecules in vitreous ice of optimal thickness is critical. Ice thickness assessment and selection of suitable holes for data collection are currently part of time-consuming preparatory routines performed on expensive electron microscopes. For this reason, we developed a method to determine ice thickness already during sample preparation using the optical camera integrated in the VitroJet. As a result, the ice thickness of buffer-suspended holes on an EM grid can be determined faithfully in the working range relevant for single particle cryo-EM.

  • learn how the automated VitroJet gives you control of the ice thickness
  • learn how the automated VitroJet gives you optical layer thickness measurements
  • learn how the VitroJet gives your team time-efficient cryo-EM structure determination

René will be at EMBL Heidelberg all days, to tell you all about the new VitroJet capabilities and customer results. Additionally, he may tell you what more is yet to come soon on our VitroJet automated sample preparation platform: build for your future needs to discover more.

We are looking forward to meeting you live at EMBL Heidelberg 2024 in Germany this second edition of this workshop. This event aims to bring the academic and industrial cryo-EM communities
together to evaluate how the use of cryo-EM has developed 10 years on from the “cryo-EM resolution revolution” and build upon the successful first edition held at EMBL in 2019.
Showcasing high-quality research in academia and industry relevant and exemplary for both cryo-EM
communities, the meeting will provide updates on recent and ongoing methodological developments.
The integration of cryo-EM in the drug-discovery workflow will also be examined. Highlights include talks from David Agard (University of California, San Francisco, USA), Claudio Ciferri (Genentech, USA), Julia Mahamid (EMBL Heidelberg, Germany), Peijun Zhang (Electron Biology Imaging Centre, UK) and other great speakers.

  • Cryo-EM in industry workflows
  • Cryo-EM applications in research
  • Cryo-EM for integrative structural biology
  • Recent developments in cryo-EM
  • Access to cryo-EM for industry and academia

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