Choosing the perfect grid for your cryo-EM experiments
Imagine finding yourself, the cryogenic electron microscopy (cryo-EM) specialist, in the heart of a bustling lab, facing the critical task of preparing your sample. Your goal: unlocking the intricate details of biomolecules with near-atomic precision. The key to success lies in many factors, e.g. the purity and concentration of your sample, buffer type, and vitrification. Also choosing the perfect grid for your specific sample can be critical. This is why we will guide you through choosing the most optimal grid for your sample preparation process, shedding light on the grid selection process and help you overcome some of the challenges and optimizing your single particle research.